BDBM50016385 4-Methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1,4]thiazepine-3-carboxylic acid methyl ester::CHEMBL158853

SMILES COC(=[OH+])C1=C(C)[N-]c2ccccc2SC1c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=UOWYLXSYWCDXAR-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016385   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50016385(4-Methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1...)
Affinity DataKd:  360nMAssay Description:Inhibition of [3H]-nitrendipine binding to calcium channels of guinea pig myocardiumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016385(4-Methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1...)
Affinity DataIC50:  140nMAssay Description:Reduction in amplitude of calcium-dependent slow-response action potential by blocking voltage sensitive calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed