BDBM50016673 CHEMBL52896::N-Hydroxy-N-methyl-2-[4-(quinolin-2-ylmethoxy)-phenyl]-acetamide

SMILES CN(O)C(=O)Cc1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key InChIKey=HIMOIVVELGFEPX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016673   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  800nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  1.00E+3nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Invitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed