BDBM50016918 CHEMBL139103::Dimethyl-[2-(naphthalen-1-yloxy)-ethyl]-amine

SMILES CN(C)CCOc1cccc2ccccc12

InChI Key InChIKey=VWPBKUKQUUEARZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016918   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016918(CHEMBL139103 | Dimethyl-[2-(naphthalen-1-yloxy)-et...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue using [3H]OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Medical College Of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016918(CHEMBL139103 | Dimethyl-[2-(naphthalen-1-yloxy)-et...)
Affinity DataKi:  94nMAssay Description:Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016918(CHEMBL139103 | Dimethyl-[2-(naphthalen-1-yloxy)-et...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat striatal membrane homogenate using [3H]5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016918(CHEMBL139103 | Dimethyl-[2-(naphthalen-1-yloxy)-et...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibitory activity against beta adrenergic receptor of rat frontal cortex homogenate using (1.0 nM) [3H]- dihydroalprenololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed