BDBM50017294 CHEMBL3288029

SMILES C[C@H]1CN(Cc2ccc(c(CN3CCOCC3)c2)-c2cccc(Oc3ncc(F)cc3C(=O)N[C@@H]3CC[C@@H](CC3)NC(=O)c3nc(C)cs3)c2)C[C@@H](C)N1

InChI Key InChIKey=BIEGUOUGXUGXQL-IDXOVHGGSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50017294   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human PDE4D using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50: >10nMAssay Description:Inhibition of human PDE4A1A using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50:  0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of rat PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017294(CHEMBL3288029)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant PDE4B at high-affinity rolipram binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed