BDBM50019156 CHEBI:10274::CHEMBL3289096

SMILES [H][C@]1([#6]-[#6][C@]2([#6])[#6]-3=[#6](-[#6]-[#6][C@@]12[#6])[C@@]1([#6])[#6]-[#6]-[#6@@H](-[#8])C([#6])([#6])[C@]1([H])[#6]-[#6]-3)[#6@H](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6](-[#8])=O

InChI Key InChIKey=DXQZEZZQGXSQDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019156   

TargetProstaglandin G/H synthase 1(Sheep)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019156(CHEMBL3289096 | CHEBI:10274)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019156(CHEMBL3289096 | CHEBI:10274)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019156(CHEMBL3289096 | CHEBI:10274)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed