BDBM50019163 Acetyl-Beta-Boswellic Acid::CHEMBL236906

SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@]5(C)CC[C@@]34C)[C@@]1(C)CC[C@@H](OC(C)=O)[C@]2(C)C(O)=O

InChI Key InChIKey=YJBVHJIKNLBFDX-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50019163   

TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed