BDBM50020585 CHEMBL3290186

SMILES COc1cc(\C=C\C(=O)\C=C\c2cc(F)c(O)c(OC)c2)cc(F)c1O

InChI Key InChIKey=FBNPNEIMXKOBBP-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020585   

TargetNuclear factor erythroid 2-related factor 2(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020585(CHEMBL3290186)
Affinity DataEC50:  3.10E+3nMAssay Description:Activation of Nrf2 transcriptional activity in human LNCaP cells after 6 hrs by luciferase reporter gene assay relative to tert-butylhydroquinoneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020585(CHEMBL3290186)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020585(CHEMBL3290186)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of STAT3 transcriptional activity in human HaCaT cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020585(CHEMBL3290186)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed