BDBM77970 3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine
SMILES CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12
InChI Key InChIKey=GDLIGKIOYRNHDA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 90 hits for monomerid = 77970
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK293 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
Affinity DataKi: 8.30nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by PDSP Ki Database
Mcneil Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by PDSP Ki Database
Mcneil Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by PDSP Ki Database
Mcneil Pharmaceutical
Curated by PDSP Ki Database
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Binding affinity towards alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 56nMAssay Description:Binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 75nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Turku
Curated by PDSP Ki Database
University Of Turku
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 5.00E+3nMAssay Description:Binding affinity towards serotonin S1 receptorMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli JM109 cellsMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Compound was evaluated for the competitive inhibition of trypanothione reduction by recombinant Trypanothione reductase from Trypanosoma cruziMore data for this Ligand-Target Pair