BDBM50026958 (cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol; Dihydrochloride::(trans) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol; Dihydrochloride::CHEMBL2448057

SMILES Cl.Cl.OCCN1CCN(CC1)C1CC(c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=XYMMYIPOWNNPDI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026958   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  600nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  10nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  210nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  2.80nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  12nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)
Affinity DataIC50:  8.20nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed