BDBM50029408 4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL343078

SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=FOLDFBZXQLCLJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029408   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029408(4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  4.5nMAssay Description:Binding affinity for 5-hydroxytryptamine 2A receptor, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029408(4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029408(4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  5.70nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed