BDBM50029668 AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US11111233, Example AZD9291::US20230322822, Compound AZD9291::US9890168, Compound AZD-9291::WO2022090481, Example osimertinib
SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12
InChI Key InChIKey=DUYJMQONPNNFPI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50029668
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuzhou Medical University
Curated by ChEMBL
Xuzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of wild type EGFR in human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuzhou Medical University
Curated by ChEMBL
Xuzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of wild type EGFR in human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuzhou Medical University
Curated by ChEMBL
Xuzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of wild type EGFR in human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuzhou Medical University
Curated by ChEMBL
Xuzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of wild type EGFR in human A-431 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair