BDBM50029778 CHEMBL264717::N-{3-[5-(4-fluorophenoxy)-2-furyl]prop-2-ynyl}-N-hydroxyurea::N-{3-[5-(4-fluorophenoxy)furan-2-yl]prop-2-ynyl}-N-hydroxyurea

SMILES NC(=O)N(O)CC#Cc1ccc(Oc2ccc(F)cc2)o1

InChI Key InChIKey=LMKILXJEWYALMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029778   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029778(CHEMBL264717 | N-{3-[5-(4-fluorophenoxy)-2-furyl]p...)
Affinity DataIC50:  60nMAssay Description:5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029778(CHEMBL264717 | N-{3-[5-(4-fluorophenoxy)-2-furyl]p...)
Affinity DataIC50:  60nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed