BDBM50030823 CHEMBL3342553

SMILES CNC(=O)O[C@H]1COc2ccc(cc2[C@@H]1NC(=O)c1ccc(F)cc1)N1CCN(CC1)C1COC1

InChI Key InChIKey=NDEBZCZEAVMSQF-GOTSBHOMSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50030823   

TargetCathepsin S(Mus musculus (Mouse))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50030823(CHEMBL3342553)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50030823(CHEMBL3342553)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair