BDBM50035734 CHEMBL1643896::RTI-229::[3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-pyrrolidin-1-yl-methanone

SMILES [H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(I)cc1)C(=O)N1CCCC1)N2C

InChI Key InChIKey=HPQILAIJSLHQQC-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035734   

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  157nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  596nMAssay Description:Affinity for norepinephrine transporter determined by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed