BDBM50049993 2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-2-(1H-indol-3-yl)-ethyl]-5-propyl-thiazole-4-carboxylic acid::CHEMBL176992

SMILES CCCc1sc(nc1C(O)=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1

InChI Key InChIKey=AMWBNAUCSURVEV-BJKOFHAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049993   

TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049993(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Endothelin-1 binding to Endothelin A receptor binding sites in MMQ cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049993(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Endothelin-3(ET-3) binding to Endothelin B receptor binding sites in porcine cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed