BDBM50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626
SMILES OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1
InChI Key InChIKey=LLBLNMUONVVVPG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 48 hits for monomerid = 50050467
Affinity DataKi: 2.40nMAssay Description:Binding affinity towards cloned human Dopamine receptor D2 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19.3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 87nMAssay Description:Compound was measured for its ability to compete with [3H]spiperone binding to the human Dopamine receptor D3 transfected in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity towards cloned human Dopamine receptor D3 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 104nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 163nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 163nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 449nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 695nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 722nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rat)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 1.52E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.52E+3nMAssay Description:Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Pig)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rat)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 6.30E+3nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Centre De Recherches De Croissy
Curated by PDSP Ki Database
Affinity DataKi: 6.57E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataEC50: 90.4nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataEC50: 4.46nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.46nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 90.4nMAssay Description:Antagonist activity at dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair