BDBM50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626

SMILES OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=LLBLNMUONVVVPG-UHFFFAOYSA-N

Data  44 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50050467   

TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  11.2nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  163nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  695nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  722nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  6.57E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataIC50:  4.46nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataIC50:  90.4nMAssay Description:Antagonist activity at dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed