BDBM50053518 4-{3-[5-Furan-3-yl-7-(3-methyl-1H-tetrazol-5-yl)-naphthalen-2-yloxymethyl]-phenyl}-tetrahydro-pyran-4-ol::CHEMBL338132

SMILES Cn1nnc(n1)-c1cc(-c2ccoc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1

InChI Key InChIKey=CKLYTSMWXULDEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053518   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053518(4-{3-[5-Furan-3-yl-7-(3-methyl-1H-tetrazol-5-yl)-n...)
Affinity DataIC50:  80nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed