BDBM50054471 (5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-amide::(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-amide::(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide::(8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-amide::AM-404::AM404::CHEMBL39878::Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-amide::N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide::N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide::cid_6604822

SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc(O)cc1

InChI Key InChIKey=IJBZOOZRAXHERC-DOFZRALJSA-N

Data  13 KI  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50054471   

TargetFatty acid-binding protein, liver(Mus musculus (Mouse))
Avanti Polar Lipids

LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  29nMAssay Description:The following fluorescent ligand displacement assays at 24 C were used to further confirm and/or determine if the cytosolic lipidic ligand "chaperon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human CB2 cannabinoid receptor using [3H]CP-55940 in HEK293 EBNA transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against G protein coupled Cannabinoid receptor 1 using [3H]WIN-55212-2 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against G protein coupled human Cannabinoid receptor 2 using [3H]CP-55940 in HEK293 EBNA transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to CB1 cannabinoid receptor using [3H]WIN-55212-2 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Martin-Luther-Universitaet

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.76E+3nMAssay Description:Tested for binding affinity to Cannabinoid receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]-CP-55,940 from Cannabinoid receptor 1 of rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Martin-Luther-Universitaet

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to vanilloid VR1 receptor using [3H]resiniferatoxin ([3H]-RTX) in rat spinal cord membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against vanilloid receptor 1 (VR1) using [3H]RTX in rat spinal cord membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataKi:  1.30E+4nMAssay Description:Compound was evaluated for its binding affinity for mouse spleen Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataEC50:  2.80E+4nMAssay Description:Stimulation of human 20S proteasome using 11 amino acid FRET peptide as substrate measured every 2 mins over 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of fatty acid amide hydrolase (FAAH) was determined using rat brain homogenates as the enzyme source and [3H]anandamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at TRPV1 in rat isolated mesenteric arteries assessed as vasorelaxation of phenylephrine-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Tryapanosom cruzi cruzain by Flexstation microplate spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Philipps-Universit£t

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50054471((5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of Tryapanosom cruzi cruzain by quantitative high throughput screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed