BDBM50056378 3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL12028
SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
InChI Key InChIKey=ZDQFLGSBTLYBIX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50056378
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...More data for this Ligand-Target Pair