BDBM50056401 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate::4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester::CHEMBL287045::SDZ 205557::SDZ-205557

SMILES CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=FFNWMBDISAYHDC-UHFFFAOYSA-N

Data  24 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50056401   

Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]-GR 113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
CNRS UPR 9023

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
CNRS UPR 9023

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
CNRS UPR 9023

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
CNRS UPR 9023

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(MOUSE)
CNRS UPR 9023

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  7.76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  7.94nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  7.94nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Université de Caen

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  126nMAssay Description:Binding affinity at 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  205nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine 1D receptor(Bos taurus (Bovine))
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  2.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(PIG)
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  3.98E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi:  6.31E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Sandoz Pharma Ltd

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed