BDBM50057233 (E)-1-[2-Hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-3-[4-(quinolin-2-ylmethoxy)-phenyl]-propenone::1-(2-hydroxy-5-(1H-tetrazol-5-yl)phenyl)-3-(4-(quinolin-2-ylmethoxy)phenyl)prop-2-en-1-one::CHEMBL11899

SMILES Oc1ccc(cc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1)-c1nnn[nH]1

InChI Key InChIKey=RQGVZKQWFKFPHB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057233   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057233((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-3-[4...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057233((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-3-[4...)
Affinity DataKd:  14nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed