BDBM50057239 2-Hydroxy-5-methyl-3-{(E)-3-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-acryloyl}-benzoic acid::2-hydroxy-5-methyl-3-(3-(3-(2-(quinolin-2-yl)vinyl)phenyl)acryloyl)benzoic acid::CHEMBL11625

SMILES Cc1cc(C(O)=O)c(O)c(c1)C(=O)\C=C\c1cccc(\C=C\c2ccc3ccccc3n2)c1

InChI Key InChIKey=VZXSJDNSOOGZCG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057239   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057239(2-hydroxy-5-methyl-3-(3-(3-(2-(quinolin-2-yl)vinyl...)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057239(2-hydroxy-5-methyl-3-(3-(3-(2-(quinolin-2-yl)vinyl...)
Affinity DataKd:  105nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed