BDBM50057260 5-Chloro-2-hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-phenyl]-acryloyl}-benzoic acid::5-chloro-2-hydroxy-3-(3-(3-(quinolin-2-ylmethoxy)phenyl)acryloyl)benzoic acid::CHEMBL11921

SMILES OC(=O)c1cc(Cl)cc(C(=O)\C=C\c2cccc(OCc3ccc4ccccc4n3)c2)c1O

InChI Key InChIKey=UKKDVBPLHLWOJP-DHZHZOJOSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057260   

TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057260(5-Chloro-2-hydroxy-3-{(E)-3-[3-(quinolin-2-ylmetho...)
Affinity DataKd:  104nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057260(5-Chloro-2-hydroxy-3-{(E)-3-[3-(quinolin-2-ylmetho...)
Affinity DataIC50:  104nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed