BDBM50057477 4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-amino]-benzoyl}-indol-1-yl)-butyric acid::4-[3-(3-{[Bis-(4-isobutyl-phenyl)-methyl]-amino}-benzoyl)-indol-1-yl]-butyric acid::CHEMBL25083::FK-143

SMILES CC(C)Cc1ccc(cc1)C(Nc1cccc(c1)C(=O)c1cn(CCCC(O)=O)c2ccccc12)c1ccc(CC(C)C)cc1

InChI Key InChIKey=LACIBZRFAYFTOV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057477   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Zeria Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Zeria Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  118nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human 5-alpha reductase 2 isozyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed