BDBM50057757 CHEMBL3323114::US9598387, Compound 121::US9969743, 121
SMILES CN(C)Cc1cccc2nc(cn12)C(=O)NCCCCN1CCN(CC1)c1cc(nc(n1)C(C)(C)C)C(F)(F)F
InChI Key InChIKey=JUJJUAKPUFHLKF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50057757
Affinity DataKi: 12nMAssay Description:Displacement of [125I]IABN from human D3R E90Q mutant expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125I]IABN from human D3R E90A mutant expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]IABN from wild type human D3R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [125I]IABN from human D3R S182I mutant expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [125I]IABN from human D3R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 27.3nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
Affinity DataKi: 27.3nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [125I]IABN from chimeric human D3 receptor possessing extracellular loop II of D2 receptor expressed in HEK293 cell membranes by gamm...More data for this Ligand-Target Pair
Affinity DataKi: 176nMAssay Description:Displacement of [125I]IABN from chimeric human D2 receptor possessing extracellular loop II of D3 receptor expressed in HEK293 cell membranes by gamm...More data for this Ligand-Target Pair
Affinity DataKi: 245nMAssay Description:Displacement of [125I]IABN from wild type human D2R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 298nMAssay Description:Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 298nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
Affinity DataKi: 298nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 281nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair