BDBM50057780 CHEMBL3323007::US9598387, Compound 125::US9969743, 125

SMILES Cc1nc(cc(n1)C(C)(C)C)N1CCN(CCCCNC(=O)c2cn3ccccc3n2)CC1

InChI Key InChIKey=MQWDTDMXDZXQGS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057780   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  134nMAssay Description:Displacement of [125I]IABN from human D3R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  134nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  134nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  4.60E+3nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  4.60E+3nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057780(CHEMBL3323007 | US9598387, Compound 125 | US996974...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed