BDBM50058099 Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzo[1,3]dioxol-5-yl)-ethyl ester::CHEMBL296927

SMILES CC(=O)OCCc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl

InChI Key InChIKey=AOMQIATVHQSAEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058099   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058099(Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5...)
Affinity DataIC50:  4.5nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058099(Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5...)
Affinity DataIC50:  2.57E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed