BDBM50058561 CHEMBL58785::N-[(2E)-3-(2-furyl)-1-methylprop-2-enyl]-N-hydroxyurea

SMILES CC(\C=C\c1ccco1)N(O)C(N)=O

InChI Key InChIKey=YQJQAHKVGNEMLM-SNAWJCMRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058561   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058561(CHEMBL58785 | N-[(2E)-3-(2-furyl)-1-methylprop-2-e...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058561(CHEMBL58785 | N-[(2E)-3-(2-furyl)-1-methylprop-2-e...)
Affinity DataIC50:  760nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed