BDBM50060965 2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione::2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::A-131701::CHEMBL40650
SMILES COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5c6ncccc6sc5c4=O)C[C@@H]3CCc12
InChI Key InChIKey=OLPQNRLJYOGSGV-WMLDXEAASA-N
Data 16 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50060965
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly activeMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1A adrenergic receptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:In vitro binding affinity using [3H]-prazosin as radioligand against alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:In vitro binding affinity using [3H]-prazosin as radioligand against alpha-1D adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1D adrenergic receptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.39nMAssay Description:In vitro binding affinity using [3H]-prazosin as radioligand against alpha-1B adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
Affinity DataKi: 6.95nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1B adrenergic receptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 13.1nMAssay Description:Binding affinity against rat Alpha-2B adrenergic receptor using [3H]-rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 16.6nMAssay Description:Binding affinity against human Alpha-2C adrenergic receptor using [3H]-rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 19.7nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]-spiroperidol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]-ketanserin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 94.9nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-2A adrenergic receptor using [3H]-rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 717nMAssay Description:Binding affinity against Dopamine receptor D1 using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.38E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1 receptor using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.87E+3nMAssay Description:Binding affinity against adrenergic receptor subtype Beta-2 adrenergic receptor using [3H]-DHA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nMAssay Description:Binding affinity against Beta-1 adrenergic receptor using [3H]-DHA as radioligandMore data for this Ligand-Target Pair