BDBM50061297 1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-2-[8-(4-methyl-piperazin-1-yl)-naphthalen-2-yloxy]-ethanone::CHEMBL129813

SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3cccc4OCCOc34)cc12

InChI Key InChIKey=ZKDTULNFGWCQJA-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061297   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061297(1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.430nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061297(1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.450nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061297(1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  14.1nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061297(1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at 5-hydroxytryptamine 1B receptor by measuring the inhibition of forskolin-stimulated cAMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed