BDBM50062599 3,5-Dimethyl-adamantan-1-ylamine::CHEMBL807::EN300-123026::MEMANTINE::Namenda::US10214478, Compound memantine

SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2

InChI Key InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N

Data  12 KI  19 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062599   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Chiba University

Curated by ChEMBL

LigandBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)Copy SMILESCopy InChI

Affinity DataIC50:  0.950nMAssay Description:Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/gluta...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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