BDBM50062599 3,5-Dimethyl-adamantan-1-ylamine::CHEMBL807::EN300-123026::MEMANTINE::Namenda::US10214478, Compound memantine
SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2
InChI Key InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50062599
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human GluN1-1a/NR2A receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rattus norvegicus (Rat))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human GluN1-1a/NR2B receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicit...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells by Ellman's methodMore data for this Ligand-Target Pair