BDBM50062599 3,5-Dimethyl-adamantan-1-ylamine::CHEMBL807::EN300-123026::MEMANTINE::Namenda::US10214478, Compound memantine
SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2
InChI Key InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50062599
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair