BDBM50062732 CHEMBL3397718

SMILES CCCC\C(=C/c1cc(OCc2cccnc2)ccc1OCc1ccc(cc1)C(F)(F)F)C(O)=O

InChI Key InChIKey=YOUIPMNBJFZTSO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062732   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataEC50:  2.32E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataEC50:  2.56E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed