BDBM50062912 CHEMBL796::Methylphenidate::alpha-phenyl-2-piperidineacetic acid methyl ester::methyl alpha-phenyl-alpha-(2-piperidyl)acetate::methyl alpha-phenyl-alpha-2-piperidinylacetate::methyl phenidylacetate::methyl phenyl(piperidin-2-yl)acetate::methylphenidan
SMILES COC(=O)C(C1CCCCN1)c1ccccc1
InChI Key InChIKey=DUGOZIWVEXMGBE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50062912
Affinity DataKi: 34nMAssay Description:Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Duquesne University
Curated by PDSP Ki Database
Duquesne University
Curated by PDSP Ki Database
Affinity DataKi: 110nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Duquesne University
Curated by PDSP Ki Database
Duquesne University
Curated by PDSP Ki Database
Affinity DataKi: 340nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.50E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]-WIN- 35,428 Binding to theDopamine Transporter in Rhesus (Macaca mulatta) orCynomolgus Monkey (Macaca fascicularis) Caudate-Putame...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Duquesne University
Curated by PDSP Ki Database
Duquesne University
Curated by PDSP Ki Database
Affinity DataIC50: 83nMAssay Description:Tested for the ability to bind stereoselectivelyand enantioselectively to the dopamine transporter(DAT); Value ranges from 34 - 83 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair