BDBM50064114 (S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-propionic acid::CHEMBL37052

SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O

InChI Key InChIKey=QRJBXCBBMUHKDQ-DQEYMECFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064114   

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed