BDBM50067678 (6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione::(6alpha)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate::17-Acetoxy-6alpha-methylprogesterone::17alpha-Hydroxy-6alpha-methylprogesterone acetate::6-alpha-Methyl-17-alpha-acetoxyprogesterone::6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate::6alpha-Methyl-17-acetoxy progesterone::6alpha-Methyl-17alpha-hydroxyprogesterone acetate::6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate::MEDROXYPROGESTERONE::Medroxyacetate progesterone::Medroxyprogesterone 17-acetate::Methylacetoxyprogesterone::Metigestrona::US9271961, MPA::medroxyprogesterone acetate

SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12

InChI Key InChIKey=PSGAAPLEWMOORI-PEINSRQWSA-N

Data  18 KI  25 IC50  2 Kd  24 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067678   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataIC50:  280nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataIC50:  1.60E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataIC50:  700nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent