BDBM50068542 CHEMBL3400826

SMILES Cc1c(NC(=O)c2ccc(cc2)C(C)(C)C)cccc1-c1cn(C)c(=O)c(Nc2ccc(cc2)C(=O)NCCCNC(=S)Nc2ccc(c(c2)C(O)=O)-c2c3ccc(O)cc3oc3cc(=O)ccc23)n1

InChI Key InChIKey=JPJLPHFCQVSFAD-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068542   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50068542(CHEMBL3400826)
Affinity DataIC50:  208nMAssay Description:Inhibition of biotinylated and activated BTK (unknown origin) using FITC-labeled Srctide peptide substrate and ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50068542(CHEMBL3400826)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to biotinylated and unactivated BTK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50068542(CHEMBL3400826)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of biotinylated and unactivated BTK (unknown origin) using FITC-labeled Srctide peptide substrate and ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed