BDBM50068775 2H-Isoquinolin-1-one::CHEMBL339695::isoquinolin-1(2H)-one
SMILES O=c1[nH]ccc2ccccc12
InChI Key InChIKey=VDBNYAPERZTOOF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50068775
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.90E+7nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assayMore data for this Ligand-Target Pair