BDBM50069364 (1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::(R)-2-(1-((1-(3-(2-(6-butyl-5-methylpyridin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetic acid::CHEMBL341547

SMILES CCCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C

InChI Key InChIKey=PNHUIGYHBQXQAN-UYOPKICRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069364   

TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069364((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50069364((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069364((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed