BDBM50070328 CHEBI:8862::Rilmenidine
SMILES C1CC1C(NC1=NCCO1)C1CC1
InChI Key InChIKey=CQXADFVORZEARL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50070328
Affinity DataKi: 11nMAssay Description:Binding affinity to I1 imidazoline binding site in Rattus norvegicus (rat) PC12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]PIC from Imidazoline-1 receptor in rat PC12 cell membrane incubated for 30 mins by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity towards human Alpha-2B adrenergic receptor by the displacement of [3H]rauwolscineMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]clonidine from imidazoline receptor I-1 of bovine chromaffin cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]RX821002 from human alpha2 adrenoceptor expressed in CHO cell membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Binding affinity towards human Alpha-2A adrenergic receptor by the displacement of [3H]rauwolscineMore data for this Ligand-Target Pair
Affinity DataKi: 288nMAssay Description:Binding affinity towards human Alpha-2C adrenergic receptor by the displacement of [3H]rauwolscineMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Displacement of [3H]RS-79948-197 from recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.03E+3nMAssay Description:Binding affinity towards human Alpha-1C adrenergic receptor by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 8.91E+3nMAssay Description:Binding affinity towards human Alpha-1A adrenergic receptor by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]idazoxan from I2 imidazoline binding sites (I2Bs) of rabbit renal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.14E+4nMAssay Description:Binding affinity towards human Alpha-1B adrenergic receptor by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataEC50: 724nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Agonistic activity towards human Alpha-2C adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 275nMAssay Description:Agonistic activity towards human Alpha-2A adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 178nMAssay Description:Agonist activity at recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair