BDBM50076792 CHEMBL10812::Lithium; (S)-2-({5-[5-(4-chloro-3-fluoro-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate
SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccc(Cl)c(F)c2)cc1-c1ccccc1C)C([O-])=O
InChI Key InChIKey=MXTDFFWHYKUZFS-NDEPHWFRSA-M
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50076792
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair