BDBM50076819 4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridine-3-sulfonic acid {(S)-1-(4-amino-phenyl)-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide::CHEMBL12506

SMILES Nc1ccc(cc1)[C@H](NS(=O)(=O)c1cnccc1N[C@H](CO)Cc1ccccc1)C(=O)N1CCC(CCF)CC1

InChI Key InChIKey=PYACADUHDHRESY-LSYYVWMOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076819   

TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  2.52E+4nMAssay Description:Binding affinity of the compound was evaluated against against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi: >8.60E+4nMAssay Description:Binding affinity of the compound was evaluated against against human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  1.15E+5nMAssay Description:Binding affinity of the compound was evaluated against against human chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed