BDBM50080797 7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-one::CHEMBL332154

SMILES O=c1ccc2ccc(CNCCNc3ccccc3)cc2o1

InChI Key InChIKey=RNNKCHJUBXFBQB-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080797   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  5.80nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  424nMAssay Description:Compound was tested for binding affinity using [3H]spiperone against cloned human Dopamine receptor D3 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  2.67E+3nMAssay Description:Compound was tested for binding affinity using [3H]prazosin against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  3.71E+3nMAssay Description:Compound was tested for binding affinity using [3H]8-OH-DPAT against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(BOVINE)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi: >4.35E+3nMAssay Description:Compound was tested for binding affinity using [3H]ketanserin against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi: >4.70E+3nMAssay Description:Compound was tested for binding affinity using [3H]MK-912 against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataIC50:  1.30nMAssay Description:Compound was tested for the inhibition of [3H]-thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed