BDBM50081974 4-(4-Benzyl-piperazin-1-yl)-7-fluoro-pyrrolo[1,2-a]quinoxaline::4-(4-benzylpiperazin-1-yl)-7-fluoropyrrolo[1,2-a]quinoxaline::CHEMBL342447

SMILES Fc1ccc2c(c1)nc(N1CCN(Cc3ccccc3)CC1)c1cccn21

InChI Key InChIKey=ZMEPAGFWARRSBT-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081974   

Target5-hydroxytryptamine receptor 3A/3B(Human)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081974BDBM50081974(4-(4-Benzyl-piperazin-1-yl)-7-fluoro-pyrrolo[1,2-a...)
Affinity DataEC50:  4.20nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081974BDBM50081974(4-(4-Benzyl-piperazin-1-yl)-7-fluoro-pyrrolo[1,2-a...)
Affinity DataIC50: 13nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed