BDBM50082851 4-(3,4-Difluoro-phenyl)-6-methyl-3-{3-[(R)-2-methyl-4-(2-nitro-phenyl)-piperazin-1-yl]-propylcarbamoyl}-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL341849

SMILES COC(=O)C1=C(C)NC(=O)N(C1c1ccc(F)c(F)c1)C(=O)NCCCN1CCN(C[C@H]1C)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=JCWKQYAUPMXURC-SMFUYQKNSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082851   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082851(4-(3,4-Difluoro-phenyl)-6-methyl-3-{3-[(R)-2-methy...)
Affinity DataKi:  0.0500nMAssay Description:In vitro binding affinity against Alpha-1A adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082851(4-(3,4-Difluoro-phenyl)-6-methyl-3-{3-[(R)-2-methy...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082851(4-(3,4-Difluoro-phenyl)-6-methyl-3-{3-[(R)-2-methy...)
Affinity DataKi:  28nMAssay Description:In vitro binding affinity against Alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed