BDBM50084419 Andrographolide::CHEBI:65408

SMILES [H][C@]12CCC(=C)[C@@H](C\C=C3/[C@H](O)COC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO

InChI Key InChIKey=BOJKULTULYSRAS-OTESTREVSA-N

Data  5 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084419   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50084419(Andrographolide | CHEBI:65408)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50084419(Andrographolide | CHEBI:65408)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human AD293 cells incubated with NF-kappaB for 16 hrs followed by compound addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50084419(Andrographolide | CHEBI:65408)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50084419(Andrographolide | CHEBI:65408)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50084419(Andrographolide | CHEBI:65408)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed