BDBM50085658 (2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::(2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol::2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol(CCPA)::2-Cl-CPA::2-chloro-N6-cyclopentyladenosine::5-(2-Chloro-6-cyclopentylamino-purin-9-yl)-tetrahydro-furan-2,3,4-triol::CCPA::CHEMBL284969::N6-Cyclopentyl-2-chloroAdo

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12

InChI Key InChIKey=XSMYYYQVWPZWIZ-UHFFFAOYSA-N

Data  68 KI  3 IC50  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50085658   

TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataIC50: 11nMAssay Description:Agonist activity at human Adenosine A3 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Mouse)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from mouse A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-HEMADO from human A3 receptor stably expressed in CHO cell membranes by radioligand competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  34nMAssay Description:Binding affinity in membrane of CHO cell stably expressing recombinant human Adenosine A3 receptor in the presence of GTPgammaS using [3H]8-ethyl-4-m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  38nMAssay Description:Bnding affinity in membrane of CHO cell stably expressing recombinant human Adenosine A3 receptor using [3H]8-ethyl-4-methyl-2-phenyl-(8R)-4,5,7,8-te...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  38nMAssay Description:Affinity for human Adenosine A3 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from human A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  38nMAssay Description:Binding affinity to Adenosine receptor A3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  38nMAssay Description:Binding affinity to human adenosine A3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards Adenosine A3 receptor (W243 mutant receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  114nMAssay Description:Binding affinity towards human Adenosine A3 receptor wild typeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  204nMAssay Description:Affinity towards Adenosine A3 receptor expressed in HEK 293 cells using [125I]AB-MECA radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  237nMAssay Description:Binding affinity to rat adenosine A3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  237nMAssay Description:Displacement of [125I]- AB-MECA from rat adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  237nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  281nMAssay Description:Inhibition of [125 I]-IABMECA binding to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  796nMAssay Description:Binding affinity towards Adenosine A3 receptor (H95A mutant receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  1.88E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed