BDBM50093160 CHEMBL263454::Derivative of piperazine-1-carboxylic acid 5-(piperazine-1-carbonyloxy)-cyclooctyl ester

SMILES NC[C@H]1CC[C@H](CNC(=O)N2CCN(CC2)C(=O)O[C@H]2CCC[C@H](CCC2)OC(=O)N2CCN(CC2)C(=O)NC[C@H]2CC[C@H](CN)CC2)CC1

InChI Key InChIKey=JFGPIRSKQQLIBV-XHNFSKJYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093160   

TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093160(CHEMBL263454 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  16nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093160(CHEMBL263454 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093160(CHEMBL263454 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093160(CHEMBL263454 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed